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Retatrutide
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Fat Loss
Research chemical
5-Amino-1MQ
Also known as: 5-Amino-1-Methylquinolinium, NNMT Inhibitor
5-Amino-1MQ is a small-molecule inhibitor of the enzyme NNMT (Nicotinamide N-Methyltransferase), which plays a major role in fat storage, NAD+ regulation, and cellular metabolism. By blocking NNMT, 5-Amino-1MQ helps increase NAD+ levels, reduce fat accumulation, support muscle growth, and improve metabolic health — making it popular for body recomposition and anti-aging.
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$50
10mg
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5-Amino-1MQ is a small-molecule inhibitor of the enzyme NNMT (Nicotinamide N-Methyltransferase), which plays a major role in fat storage, NAD+ regulation, and cellular metabolism. By blocking NNMT, 5-Amino-1MQ helps increase NAD+ levels, reduce fat accumulation, support muscle growth, and improve metabolic health — making it popular for body recomposition and anti-aging.
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Half-Life
Estimated several hours
Common Dose
50–150 mg per day
Route
Subcutaneous injection
Frequency
Once daily
Mechanism of Action
NNMT consumes nicotinamide (a NAD+ precursor) and SAM, methylating nicotinamide and depleting cellular NAD+. Elevated NNMT activity is linked to obesity, insulin resistance, and muscle wasting. By inhibiting NNMT, 5-Amino-1MQ raises NAD+ availability, restores methyl donor balance, promotes lipolysis in white adipose tissue, and supports muscle satellite cell function and regeneration.
Reported Benefits
- ✦Increased fat loss, especially visceral and subcutaneous fat
- ✦Elevated NAD+ levels
- ✦Improved insulin sensitivity
- ✦Enhanced muscle growth and regeneration
- ✦Supports body recomposition (fat loss + muscle preservation)
- ✦Anti-aging and metabolic health support
- ✦May reduce age-related muscle decline
Dosage Protocol
Common dose50–150 mg per day
Range50–200 mg per day depending on goals and tolerance
FrequencyOnce daily, typically in the morning
AdministrationSubcutaneous injection
Notes
Available in a 10 mg vial. Reconstitute with bacteriostatic water per the applicable research protocol.
Research Status
Pre-clinical research demonstrates strong fat loss and muscle-supporting effects. Limited human clinical data. Used in research and longevity protocols.
Storage
Lyophilized: refrigerate. Reconstituted: refrigerate, use within 30 days.
Legal Status
Research chemical. Not approved for human therapeutic use.
Commonly Stacked With
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Quick Reference
1 mg= 1,000 mcg
1 mL= 100 units (on a 100u syringe)
1 mL= 1 cc
Common reconstitution1–3 mL BAC water per vial
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Research use only. This tool is a mathematical reference for trained laboratory personnel. It does not recommend a dose, injection volume, treatment, or human use. Always follow your approved protocol, product documentation, and applicable regulations.
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For laboratory research purposes only. Not for human use. Not medical advice.