Directory /Tirzepatide

Fat Loss FDA-approved prescription drug (Mounjaro for diabetes, Zepbound for weight loss)

Tirzepatide

Also known as: Mounjaro, Zepbound, LY3298176

Tirzepatide is a dual GLP-1 / GIP receptor agonist developed by Eli Lilly and FDA-approved as Mounjaro (for type 2 diabetes) and Zepbound (for weight loss). In clinical trials, it produced ~15–22% body weight reduction — the most effective weight-loss medication approved to date. Used for type 2 diabetes, obesity, and metabolic syndrome.

Size

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$60

10mg

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Half-Life

~5 days

Common Dose

Start 2.5 mg/week, titrate up by 2.5 mg every 4 weeks to 5–15 mg/week

Route

Subcutaneous injection (abdomen

Frequency

Once weekly subcutaneous injection

Mechanism of Action

Tirzepatide activates two receptors simultaneously: GLP-1 (suppresses appetite, slows gastric emptying, improves insulin secretion) and GIP (enhances insulin sensitivity and supports fat metabolism). The dual-agonist effect produces greater weight loss and glycemic control than GLP-1 monotherapy (e.g., Semaglutide).

Reported Benefits

✦Significant weight loss (~15–22% body weight)
✦Excellent blood sugar control
✦Reduced appetite and cravings
✦Improved insulin sensitivity
✦Cardiovascular risk reduction
✦Better lipid profile
✦FDA-approved for type 2 diabetes and obesity

Dosage Protocol

Common doseStart 2.5 mg/week, titrate up by 2.5 mg every 4 weeks to 5–15 mg/week

Range2.5–15 mg per week (FDA-approved range)

FrequencyOnce weekly subcutaneous injection

AdministrationSubcutaneous injection (abdomen, thigh, or upper arm)

Notes

Available in 10 mg and 20 mg vials. A 10 mg vial reconstituted with 2 mL bac water yields 5 mg/mL. Always titrate slowly to minimize GI side effects. Pair with adequate protein intake and resistance training to preserve muscle mass during weight loss.

Research Status

FDA-approved (Mounjaro / Zepbound). Multiple ongoing trials for additional indications including heart failure and NASH.

Storage

Lyophilized: refrigerate. Reconstituted: refrigerate, use within 30 days.

Legal Status

FDA-approved prescription drug (Mounjaro for diabetes, Zepbound for weight loss).

Commonly Stacked With

Tesamorelin 5-Amino-1MQ

5-Amino-1MQ

Fat Loss

Tesamorelin

Growth Hormone Secretagogues

Dose Calculator

Pre-filled with Tirzepatide's vial size. Enter your water volume and desired dose to see exactly how many units to draw.

Peptide in Vial (mg)

Total milligrams in the vial (check the label)

Water Added (mL)

Bacteriostatic water added to reconstitute

Desired Dose (mcg)

Micrograms you want per injection

Syringe Size

Insulin syringe capacity

Results

Concentration

—mcg/mL

Volume to Inject

—mL

Draw to Mark

—units

Doses per Vial

—doses

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Quick Reference

1 mg= 1,000 mcg

1 mL= 100 units (on a 100u syringe)

1 mL= 1 cc

Common reconstitution1–3 mL BAC water per vial

How long will this vial last?

Choose the vial strength, enter the amount used per draw, and add the number of draws per week to estimate how long it will last.

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Research use only. This tool is a mathematical reference for trained laboratory personnel. It does not recommend a dose, injection volume, treatment, or human use. Always follow your approved protocol, product documentation, and applicable regulations.