Up to15% off
Third-party tested
Third-party tested
5-Amino-1MQ
Fat Loss
10mg
$50
Fat Loss
Investigational drug (Phase III)
Retatrutide
Also known as: LY3437943, Triple Agonist
Retatrutide is a next-generation triple agonist of the GLP-1, GIP, and glucagon receptors — currently in Phase III clinical trials by Eli Lilly. It is the most powerful weight-loss peptide developed to date, producing 20–25%+ body weight reduction in Phase II trials (vs ~15% for Tirzepatide). The addition of glucagon receptor agonism increases energy expenditure on top of appetite suppression.
Size
Bundle & Save
$90
10mg
Free Xpresspost shipping on orders over $199
Retatrutide is a next-generation triple agonist of the GLP-1, GIP, and glucagon receptors — currently in Phase III clinical trials by Eli Lilly. It is the most powerful weight-loss peptide developed to date, producing 20–25%+ body weight reduction in Phase II trials (vs ~15% for Tirzepatide). The addition of glucagon receptor agonism increases energy expenditure on top of appetite suppression.
Third-Party TestedEvery batch verified
Ships from CanadaFast domestic delivery
Free XpresspostOn orders over $199
Secure CheckoutSafe & private
Half-Life
~6 days
Common Dose
Start 2 mg/week, titrate up by 2 mg every 4 weeks to 8–12 mg/week
Route
Subcutaneous injection (abdomen
Frequency
Once weekly subcutaneous injection
Mechanism of Action
Retatrutide simultaneously activates three receptors: GLP-1 (suppresses appetite, slows gastric emptying, improves glucose control), GIP (enhances insulin sensitivity and supports fat metabolism), and glucagon (increases resting energy expenditure and promotes lipolysis). The combined effect produces appetite suppression PLUS increased metabolic rate — a unique combination among incretin therapies.
Reported Benefits
- ✦Most powerful weight-loss peptide currently in development (20–25%+ body weight loss)
- ✦Triple-receptor mechanism (GLP-1 + GIP + glucagon)
- ✦Increases energy expenditure (glucagon effect)
- ✦Strong appetite suppression
- ✦Improved insulin sensitivity and glucose control
- ✦Improved cardiometabolic markers
- ✦Effective for severe obesity and metabolic syndrome
Dosage Protocol
Common doseStart 2 mg/week, titrate up by 2 mg every 4 weeks to 8–12 mg/week
Range2–12 mg per week (clinical trials tested up to 12 mg)
FrequencyOnce weekly subcutaneous injection
AdministrationSubcutaneous injection (abdomen, thigh, or upper arm)
Notes
Available in 10 mg, 20 mg, and 30 mg vial sizes. Always titrate slowly to minimize GI side effects. 10 mg vial reconstituted with 2 mL bac water = 5 mg/mL (40 units = 2 mg, 80 units = 4 mg). Pair with adequate protein intake and resistance training to preserve muscle.
Research Status
Phase III clinical trials. Not yet FDA-approved. Strongest weight-loss results in any incretin trial to date.
Storage
Lyophilized: refrigerate. Reconstituted: refrigerate, use within 30 days.
Legal Status
Investigational drug (Phase III). Not yet approved. Available as research chemical.
Commonly Stacked With
Dose Calculator
Pre-filled with Retatrutide's vial size. Enter your water volume and desired dose to see exactly how many units to draw.
Total milligrams in the vial (check the label)
Bacteriostatic water added to reconstitute
Micrograms you want per injection
Insulin syringe capacity
Results
Concentration
—mcg/mL
Volume to Inject
—mL
Draw to Mark
—units
Doses per Vial
—doses
Fill in all fields above to see your results.
Quick Reference
1 mg= 1,000 mcg
1 mL= 100 units (on a 100u syringe)
1 mL= 1 cc
Common reconstitution1–3 mL BAC water per vial
How long will this vial last?
Choose the vial strength, enter the amount used per draw, and add the number of draws per week to estimate how long it will last.
Estimated duration
—
Email me this protocol
Keep a copy of these calculated values for your laboratory records.
This will open your default email app to send the protocol. Automated email delivery can be connected separately.
Research use only. This tool is a mathematical reference for trained laboratory personnel. It does not recommend a dose, injection volume, treatment, or human use. Always follow your approved protocol, product documentation, and applicable regulations.
Explore the catalogue
You may also like
Get 25% off your first order
Drop your email and we’ll unlock a one-time 25% discount code.
Zenova Peptides
For laboratory research purposes only. Not for human use. Not medical advice.