Anti-Aging Available via compounding pharmacies and IV therapy clinics

NAD+

Also known as: Nicotinamide Adenine Dinucleotide, NAD Plus

NAD+ is a critical coenzyme found in every cell of the body, essential for energy production, DNA repair, and cellular signaling. Levels decline dramatically with age, contributing to fatigue, metabolic decline, and accelerated aging. Injectable NAD+ bypasses poor oral absorption to directly restore cellular NAD+ levels — popular for energy, cognitive function, recovery, and longevity.

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$50

500mg

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Half-Life

Plasma half-life varies; cellular effects persist

Common Dose

50–250 mg per session (SC); 250–500 mg per IV session

Route

Subcutaneous injection or IV infusion (IV most effective for large doses)

Frequency

Daily SC microdoses or 1–3x weekly larger doses

Mechanism of Action

NAD+ is required for over 500 enzymatic reactions, including those of sirtuins (longevity proteins) and PARPs (DNA repair enzymes). It is essential for mitochondrial electron transport and ATP production. Restoring NAD+ levels reactivates sirtuin-mediated longevity pathways, improves mitochondrial function, supports DNA repair, and enhances overall cellular metabolism.

Reported Benefits

✦Increased energy and reduced fatigue
✦Cognitive enhancement and mental clarity
✦Anti-aging via sirtuin activation
✦DNA repair support
✦Mitochondrial health and biogenesis
✦Improved metabolic function
✦Used in addiction recovery and chronic fatigue protocols
✦Athletic recovery and performance

Dosage Protocol

Common dose50–250 mg per session (SC); 250–500 mg per IV session

Range50–1000 mg depending on route and goal

FrequencyDaily SC microdoses or 1–3x weekly larger doses

AdministrationSubcutaneous injection or IV infusion (IV most effective for large doses)

Notes

500 mg vial — reconstitute per provider protocol. SC dosing: start with 50–100 mg and titrate up to assess tolerance (flushing is common). IV infusions typically run 250–500 mg over 1–4 hours. Cycle 4–8 weeks or use as needed for energy/recovery.

Research Status

Active research in aging, neurodegenerative disease, and metabolic health. Used clinically in IV therapy and addiction recovery.

Storage

Lyophilized: refrigerate, protect from light. Reconstituted: refrigerate, use within 14 days.

Legal Status

Available via compounding pharmacies and IV therapy clinics. Not FDA-approved as a drug.

Commonly Stacked With

Glutathione SS-31 5-Amino-1MQ MOTS-c

5-Amino-1MQ

Fat Loss

Glutathione

Anti-Aging

MOTS-c

Anti-Aging

SS-31

Anti-Aging

Dose Calculator

Pre-filled with NAD+'s vial size. Enter your water volume and desired dose to see exactly how many units to draw.

Peptide in Vial (mg)

Total milligrams in the vial (check the label)

Water Added (mL)

Bacteriostatic water added to reconstitute

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Micrograms you want per injection

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Results

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Quick Reference

1 mg= 1,000 mcg

1 mL= 100 units (on a 100u syringe)

1 mL= 1 cc

Common reconstitution1–3 mL BAC water per vial

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Research use only. This tool is a mathematical reference for trained laboratory personnel. It does not recommend a dose, injection volume, treatment, or human use. Always follow your approved protocol, product documentation, and applicable regulations.