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Anti-Aging Investigational drug

SS-31

Also known as: Elamipretide, Bendavia, MTP-131

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$70

10mg

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SS-31 (Elamipretide) is a mitochondria-targeted peptide that selectively binds to cardiolipin on the inner mitochondrial membrane. It restores mitochondrial function, reduces oxidative stress, and protects against mitochondrial dysfunction — a key driver of aging and many chronic diseases. Currently in clinical trials for several mitochondrial diseases.
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Half-Life

~3–5 hours

Common Dose

1–5 mg per day

Route

Subcutaneous injection

Frequency

Once daily

Mechanism of Action

SS-31 binds cardiolipin, a phospholipid unique to the inner mitochondrial membrane that is essential for electron transport chain function. It stabilizes cardiolipin, restores efficient ATP production, reduces reactive oxygen species (ROS), and prevents cytochrome-c release (a trigger of apoptosis). This makes failing mitochondria function more like young, healthy ones.

Reported Benefits

  • Restores mitochondrial function
  • Reduces oxidative stress and ROS
  • Increased energy and reduced fatigue
  • Anti-aging effects at the cellular level
  • Cardioprotective (studied for heart failure, ischemia)
  • May help mitochondrial myopathies
  • Supports exercise capacity and recovery
  • Neuroprotective potential

Dosage Protocol

Common dose1–5 mg per day
Range1–10 mg per day depending on protocol
FrequencyOnce daily
AdministrationSubcutaneous injection

Notes

10 mg vial — reconstitute with 2 mL bac water → 5 mg/mL: 10 units (0.1 mL) = 500 mcg, 20 units = 1 mg. Cycle 4–8 weeks or longer. Often used in combination with NAD+ and Glutathione for comprehensive mitochondrial support.

Research Status

Multiple human clinical trials (Phase II/III) for mitochondrial myopathies, cardiac conditions, and rare diseases.

Storage

Lyophilized: refrigerate, protect from light. Reconstituted: refrigerate, use within 30 days.

Legal Status

Investigational drug. Not yet FDA-approved.

Dose Calculator

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Concentration

mcg/mL

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mL

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Quick Reference

1 mg= 1,000 mcg
1 mL= 100 units (on a 100u syringe)
1 mL= 1 cc
Common reconstitution1–3 mL BAC water per vial

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Research use only. This tool is a mathematical reference for trained laboratory personnel. It does not recommend a dose, injection volume, treatment, or human use. Always follow your approved protocol, product documentation, and applicable regulations.

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