5-Amino-1MQ
Also known as: 5-Amino-1-Methylquinolinium, NNMT Inhibitor
5-Amino-1MQ is a small-molecule inhibitor of the enzyme NNMT (Nicotinamide N-Methyltransferase), which plays a major role in fat storage, NAD+ regulation, and cellular metabolism. By blocking NNMT, 5-Amino-1MQ helps increase NAD+ levels, reduce fat accumulation, support muscle growth, and improve metabolic health — making it popular for body recomposition and anti-aging.
Research Use Only
Pricing
10-Pack Bundle Save 20%
Credit card accepted · For research & educational use only — not for human consumption.
Half-Life
Estimated several hours
Common Dose
50–150 mg per day
Route
Subcutaneous injection
Frequency
Once daily
Mechanism of Action
NNMT consumes nicotinamide (a NAD+ precursor) and SAM, methylating nicotinamide and depleting cellular NAD+. Elevated NNMT activity is linked to obesity, insulin resistance, and muscle wasting. By inhibiting NNMT, 5-Amino-1MQ raises NAD+ availability, restores methyl donor balance, promotes lipolysis in white adipose tissue, and supports muscle satellite cell function and regeneration.
Reported Benefits
- ✦Increased fat loss, especially visceral and subcutaneous fat
- ✦Elevated NAD+ levels
- ✦Improved insulin sensitivity
- ✦Enhanced muscle growth and regeneration
- ✦Supports body recomposition (fat loss + muscle preservation)
- ✦Anti-aging and metabolic health support
- ✦May reduce age-related muscle decline
Side Effects
- !Generally well-tolerated in studies
- !Mild injection site irritation
- !Possible mild GI discomfort
- !Limited long-term human safety data
Dosage Protocol
Notes
5 mg vial — reconstitute with bacteriostatic water per provider protocol. Often run 4–12 week cycles. Best paired with strength training and protein-adequate diet for body recomposition results.
Research Status
Pre-clinical research demonstrates strong fat loss and muscle-supporting effects. Limited human clinical data. Used in research and longevity protocols.
Contraindications
- ✕Pregnancy and breastfeeding
- ✕Known hypersensitivity
- ✕Caution with other metabolic-altering medications
Storage
Lyophilized: refrigerate. Reconstituted: refrigerate, use within 30 days.
Legal Status
Research chemical. Not approved for human therapeutic use.
Dose Calculator
Pre-filled with 5-Amino-1MQ's vial size. Enter your water volume and desired dose to see exactly how many units to draw.
Total milligrams in the vial (check the label)
Bacteriostatic water added to reconstitute
Micrograms you want per injection
Insulin syringe capacity
Results
Concentration
—mcg/mL
Volume to Inject
—mL
Draw to Mark
—units
Doses per Vial
—doses
Fill in all fields above to see your results.
